Optimizing Fuel Strategies for CAR-T Cell Transduction & Efficacy
Roddy O'Connor, Ph.D.
Research Assistant Professor
University of Pennsylvania, School of Medicine
Dr. O'Connor is a Research Assistant Professor at the Center for Cellular Immunotherapies at the University of Pennsylvania where he studies the metabolism and functionality of CAR-T cells.
In this video, you will learn:
- The concepts of adoptive immunotherapy
- The differences between design and functionality of first and second generation CARs
- The role of glucose consumption in T cell expansion/differentiation
- The rationale for studying media conditions and their effect on CAR-T activity/efficacy