Optimizing Fuel Strategies for CAR-T Cell Transduction & Efficacy

Presented by:

Roddy O'Connor, Ph.D.

Research Assistant Professor
University of Pennsylvania, School of Medicine

Dr. O'Connor is a Research Assistant Professor at the Center for Cellular Immunotherapies at the University of Pennsylvania where he studies the metabolism and functionality of CAR-T cells.

In this video, you will learn:

• The concepts of adoptive immunotherapy
• The differences between design and functionality of first and second generation CARs
• The role of glucose consumption in T cell expansion/differentiation
• The rationale for studying media conditions and their effect on CAR-T activity/efficacy